Esobrint tablets 40mg are used to treat conditions caused by gastric reflux, which is when the acidic contents of the stomach flow back into the oesophagus because the sphincter (muscle at the junction of the oesophagus and stomach) that normally acts as a one-way valve and prevents backflow of stomach contents, does not function properly or is damaged.  Gastroesophageal reflux disease (GORD), as this condition is known, causes symptoms like heartburn and dyspepsia (indigestion and abdominal pain), and can damage the oesophagus causing inflammation (oesophagitis).  Esobrint 40 is also used to treat and prevent peptic ulcers in the stomach (gastric ulcers or damage to the stomach lining) and duodenum (duodenal ulcers or damage to the lining of the upper intestine); and gastric ulcers caused by use of nonsteroidal anti-inflammatory drugs (NSAID); also, as combination therapy to treat gastric ulcers that are caused by infection of the stomach with the bacterium Helicobacter pylori, in conjunction with using antibiotics.  Esobrint 40 is also used to treat symptoms of acid-related dyspepsia that can be caused by eating high fat or acidic foods, or Zollinger-Ellison syndrome in which increased levels of the hormone gastrin causes an excessive production of gastric acid.

Esobrint tablets 40mg contain esomeprazole, a proton pump inhibitor that is used to treat conditions caused by excess gastric acid, by reducing the amount of gastric acid released into the stomach.  Stomach acid is needed for digestion of proteins in your diet and is made by the parietal cells of the stomach wall.  Gastric acid production is dependent on the action of the enzyme H⁺/K⁺-ATPase, which is the proton pump responsible for pumping positive hydrogen ions out of the cells into the stomach, which increases the acidity of the stomach contents.  Esomeprazole in Esobrint 40 inhibits the functioning of the H⁺/K⁺-ATPase, which prevents acid secretion by blocking the source of acid production.  This action of esomeprazole reduces the acidity of the stomach contents, which reduces the acid damage that can be caused by gastroesophageal reflux disease (GORD) and oesophagitis and relieves symptoms caused by excess gastric acid like heartburn and dyspepsia.  By inhibiting gastric acid secretion Esobrint 40 also help prevent the formation of gastric (stomach) and duodenal (upper intestine) peptic ulcers and also helps ulcers and damage caused by gastric reflux to heal. 

Esobrint tablets 40mg contain the active ingredient esomeprazole, which is a proton pump inhibitor that is used to treat conditions caused by excess gastric acid secretion. Esobrint also contains the following inactive ingredients: Isopropyl alcohol, dichloromethane, acryl ezee white(93058751), colloidal silicon dioxide, magnesium stearate, p.e.g-6000, purified talc, titanium dioxide, h.p.m.c (e15), purified water, microcrystalline cellulose, croscarmellose sodium, ethyl cellulose (7cps), colour iron oxide red and hydroxy propyl cellulose.

Esobrint tablets 40mg contain esomeprazole, which is used to treat conditions caused by gastroesophageal reflux disease (GORD).  Gastric reflux is when the acidic contents of the stomach flow back into the oesophagus because the sphincter (muscle at the junction of the oesophagus and stomach) that normally acts as a one-way valve and prevents backflow of stomach contents, does not function properly or is damaged.  Symptoms caused by gastric reflux include heartburn and dyspepsia (indigestion and abdominal pain), and damage to the oesophagus causing inflammation (oesophagitis).  Esomeprazole in Esobrint tablets 40mg reduces acid secretion by parietal cells of the stomach wall, by blocking the action of the enzyme H⁺/K⁺-ATPase, which is responsible for acid production.  This action of esomeprazole reduces the acidity of the stomach contents, which reduces the acid damage that can be caused by gastroesophageal reflux disease (GORD) and oesophagitis, relieves symptoms caused by excess gastric acid like heartburn and dyspepsia; as well as helping damaged tissues caused by excess acid to heal.

Esobrint tablets 40mg contain the active ingredient esomeprazole, which is used to treat and prevent prevent peptic ulcers in the stomach (gastric ulcers or damage to the stomach lining) and duodenum (duodenal ulcers or damage to the lining of the upper intestine), caused by excess secretion of gastric acid; and gastric ulcers caused by use of nonsteroidal anti-inflammatory drugs (NSAID).  Esobrint tablets 40mg are also used as combination therapy to treat and prevent gastric ulcers that are caused by infection of the stomach with the bacterium Helicobacter pylori, in conjunction with using antibiotics.  Esomeprazole in Esobrint tablets 40mg reduces acid secretion by parietal cells of the stomach wall, by blocking the action of the enzyme H⁺/K⁺-ATPase, which responsible for acid production.  This action of esomeprazole reduces the acidity of the stomach contents, which reduces the acid damage to the stomach wall and allows ulcers that have already developed to heal.

The most commonly reported side effects when taking Esobrint include, include constipation, nausea, vomiting, diarrhoea, wind (flatulence), headache, dry mouth, skin rash, dizziness, sensation of tingling in the skin (paraesthesia), insomnia.

You should not use Esobrint 40 if you:

• are allergic to esomeprazole or any ingredients in Esobrint
• are taking medicines that interact with Esobrint including: the antifungals ketoconazole and itraconazole, the anticoagulant warfarin, phenytoin for epilepsy, the antiretroviral atazanavir, the antibiotic clarithromycin, the immunosuppressive tacrolimus, the sedative diazepam

You should take your Esobrint tablets 40mg with a glass of water at least one hour before a meal.  You should continue to take your Esobrint tablets 40mg for as long as recommended by your doctor, usually for a few weeks to 6 months, depending on the condition you are being treated for. 

You should continue to take your Esobrint tablets 40mg for as long as recommended by your doctor, usually for a few weeks to 6 months, depending on the condition you are being treated for. 

If you miss a dose of Esobrint 40 take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

You should store your Esobrint tablets 40mg below 25°C in a cool dry place, well out of reach of children.