Pomisol (Ofloxacin/Clotrimazole/Betamethasone/Lignocaine 0.3%/1%/0.025%/2%) Ear Drops

Pomisol Ear Drops general information

What is Pomisol Ear Drops used for?

Pomisol Ear Drops are a combination medication used as a topical treatment for chronic and acute otitis externa in dogs; also, to prevent acute exacerbations of recurrent otitis externa.  Otitis externa is an infection of the outer ear that is caused by fungi and/or bacteria.  Pomisol Ear Drops are also effective for treating inflammation that is caused by the infection and helps relieve symptoms including itching, discomfort, redness and swelling.  Acute otitis externa can be extremely painful for dogs and Pomisol Ear Drops helps relieve the pain by numbing the area around the infection.

How does Pomisol Ear Drops work?

Pomisol Ear Drops contain a combination of three topical medications used together to treat otitis externa in dogs.  Ofloxacin in Pomisol Ear Drops is a fluoroquinolone antibiotic and is effective against a wide range of susceptible bacteria that can cause ear infection in dogs, including Pseudomonas aeruginosa, enterococcus faecalis and coagulase positive staphylococci.  It works by inhibiting the DNA topoisomerase II (DNA-gyrase) and DNA topoisomerase IV enzymes that are needed for the synthesis of bacterial DNA, which prevents bacterial replication and kills the bacteria. Clotrimazole in Pomisol Ear Drops is a broad spectrum antifungal used to treat fungal infections of the skin.  It is effective against the yeast Malassezia pachydermatis (formerly Pityrosporum canis) that causes ear infections in dogs; also against Candida that causes yeast infections and Tinea that causes ringworm.  Clotrimazole in Pomisol Ear Drops works by inhibiting the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells.  This weakens the fungal cell membrane causing the cell contents to leak out killing the fungus.  Betamethasone in Pomisol Ear Drops is synthetic corticosteroid, with anti-inflammatory and anti-pruritic activity that works by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes.  Pomisol Ear Drops also contain lignocaine, a fast-acting local anaesthetic.  Lignocaine in Pomisol Ear Drops works by acting as a nerve block and numbing the local area of application.  The combination of components in Pomisol Ear Drops work together to fight the infection that causes otitis; they also help relieve symptoms of inflammation caused by the infection and reduce the sensations of pain and itching.   

What does Pomisol Ear Drops contain?

Pomisol Ear Drops contain the active ingredients Ofloxacin (0.3%) Clotrimazole (1%) Betamethasone dipropionate (0.025%) and Lignocaine (2%) w/v in each 1ml of suspension.  

Treating otitis externa in dogs with Pomisol Ear Drops

Pomisol Ear Drops contain a combination of active ingredients that work together to treat chronic and acute otitis externa in dogs, which is infection and inflammation of the outer ear, caused by a yeast fungal infection and/or a bacterial infection. Pomisol Ear Drops are also effective for treating inflammation that is caused by the infection and helps relieve symptoms including itching, discomfort, redness and swelling.  Ofloxacin in Pomisol Ear Drops is an antibiotic effective against a wide range of susceptible bacteria that can cause ear infection in dogs, and works by inhibiting the specific enzymes needed for synthesis of bacterial DNA, which prevents bacterial replication and kills the bacteria. Clotrimazole in Pomisol Ear Drops is a broad spectrum antifungal that is effective against yeasts and fungi that cause ear infections in dogs.  It works by inhibiting the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells, which weakens the fungal cell membrane causing the cell contents to leak out killing the fungus.  Betamethasone in Pomisol Ear Drops is a topical steroid that works as an effective anti-inflammatory by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes.  Lignocaine in Pomisol Ear Drops is a fast-acting local anaesthetic and works by acting as a nerve block and numbing the local area of application.  The combination of components in Pomisol Ear Drops work together to fight the infection that causes otitis; they also help relieve symptoms of inflammation caused by the infection and reduce the sensations of pain and itching.   

What are the side effects of Pomisol Ear Drops?

The most commonly reported side effects when taking Pomisol Ear Drops include deafness or partial hearing loss and erythematous lesions (red scaly patches on the skin); also symptoms of long-term corticosteroid use like immunosuppression. 

When should Pomisol Ear Drops not be used?

You should not use Pomisol Ear Drops if your dog:

• is allergic to Ofloxacin, Clotrimazole, Betamethasone, Lignocaine or any ingredients in Pomisol Ear Drops
• has a perforated eardrum
• is less than 4 months old as joint damage can occur in young animals that are still growing
• is pregnant or lactating

How should Pomisol Ear Drops be given?

You should clean and dry your dog’s ear before applying Pomisol Ear Drops, remove any debris or crusting with a non-irritable solution and clip away any hair that would get in the way of treatment.  Shake well before use, then add 8-10 drops of Pomisol Ear Drops into your dog’s ear, depending on their size and massage the ear to ensure it has penetrated into the ear and distributed evenly.  Avoid contact with the eyes. You should give Pomisol Ear Drops to your dog once daily for 7 days but no longer as continued use could prevent wound healing.  

How long should you use Pomisol Ear Drops?

You should give Pomisol Ear Drops to your dog once daily for 7 days, or as recommended by your veterinarian, but no longer as continued use could prevent wound healing. 

Missed dose of Pomisol Ear Drops

If you miss a dose of Pomisol Ear Drops give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Pomisol Ear Drops be stored?

You should store your Pomisol Ear Drops below 25°C in a cool dry place and use within one month.