Cobix 200mg (Celecoxib)

Cobix general information

What is Cobix used for?

Cobix capsules 200mg are used to treat chronic inflammatory diseases such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, to reduce pain, inflammation, tenderness, stiffness and swelling in the affected joints. They are also used for the management of acute pain and treatment of dysmenorrhea (menstrual pain), when sufficient pain relief from other medications has not been achieved. Cobix capsules 200mg does not cure arthritic disease but can relieve symptoms of pain and inflammation and improve the functional use of affected joints.

How does Cobix work?

Cobix capsules 200mg contain celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of specific chemicals called prostaglandins (PG) that mediate inflammation. Celecoxib in Cobix capsules 200mg is a specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory prostaglandins like PGE2, which causes pain, swelling and other symptoms of inflammation. Celecoxib also has anti-pyretic action (reduces fever), but has no effect on the cyclooxygenase 1 enzyme (COX-1) that is needed for normal cellular processes. By inhibiting the action of COX-2 Cobix capsules 200mg relieve the symptoms of inflammation, including pain, swelling, and joint stiffness.

What does Cobix contain?

Cobix capsules 200mg contain the active ingredient celecoxib, a nonsteroidal anti-inflammatory drug (NSAID) and specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that reduces pain and inflammation.

Treating arthritis with Cobix

Cobix capsules 200mg contain celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) and a specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory chemicals called prostaglandins (PG), particularly PGE2. Osteoarthritis and rheumatoid arthritis are chronic inflammatory diseases in which the joints become inflamed, swollen and painful. Celecoxib in Cobix capsules 200mg help relieve the pain, swelling and other symptoms of inflammation by inhibiting the action of COX-2 therefore blocking PGE2 production. This action reduces pain and inflammation, and improves the functional use of the arthritic joint.

Cobix for pain and inflammation

Cobix capsules 200mg contain celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) and a specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory chemicals called prostaglandins (PG), particularly PGE2. Cobix capsules 200mg are used to treat chronic inflammatory diseases such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, to reduce pain, inflammation, tenderness, stiffness and swelling in the affected joints. They are also used for the management of acute pain and treatment of dysmenorrhea (menstrual pain) in people who have not been able to achieve sufficient pain relief from other medications.

What are the side effects of Cobix?

The most commonly reported side effects when taking Cobix capsules 200mg are gastrointestinal and include: upset stomach or stomach pain, diarrhoea, indigestion, bloating wind. Other side effects include: dizziness; sinusitis and upper respiratory tract infection; blurred vision; skin rash and itching; swollen hands, ankles and feet. More serious but rare side effects include gastric ulceration and bleeding and cardiovascular events including heart attack.

What are the health risks when taking Cobix?

Cobix capsules 200mg have been associated with increased risk of gastric ulceration and bleeding and cardiovascular events including heart attack, although these events are rare.

When should Cobix not be taken?

You should not use Cobix capsules 200mg if you:

• are allergic to celecoxib, aspirin or any other nonsteroidal anti-inflammatory drug (NSAID), or any ingredients in Cobix capsules 100mg
• have an allergy to sulphonamides
• have an ulcer, gastric bleeding, irritable bowel disease or heart failure
• have liver or kidney disease
• are taking medications that interact with Cobix, including: other NSAIDs, aspirin, anticoagulants like warfarin, oral corticosteroids, the antifungal drug fluconazole, diuretics like furosemide, lithium for depression, ACE inhibitors for high blood pressure, antacids for indigestion.

How should Cobix be taken?

You should take your Cobix capsules 200mg once or twice daily, with or without food. However, if your Cobix capsules upset your stomach, then you should take them with food. The dose you take and for how long depends on what you are being treated for and as recommended by your doctor, which may be for a few days, several weeks or longer.

How long should you take Cobix?

You should continue to take your Cobix capsules 200mg for as long as recommended by your doctor, which may be for a few days, several weeks or longer, depending on what you are being treated for.

Missed dose of Cobix

If you miss a dose of Cobix capsules 200mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Cobix be stored?

You should keep your Cobix capsules 200mg in their blister pack until it is time to take them. Store in a cool, dry place at room temperature at or below 25°C.